CH- Guest Seminar:Dr Sayantan Dutta on March 24, 4 pm @ MSB 241

CH- Guest Seminar:Dr Sayantan Dutta on March 24, 4 pm @ MSB 241

When:
March 24, 2023 @ 4:00 am ā€“ 5:00 am
2023-03-24T04:00:00+05:30
2023-03-24T05:00:00+05:30
Where:
MSB 241
Contact:
Prof. Abhijit Deshpande P
04422574150

Title:


Chemical Engineering Models: a Versatile Toolbox for Interpreting Biological Data

Abstract:
Living cells and tissues are complex machineries, where biochemical signaling pathways, genetic networks, molecular motors, and cytoskeletal elements orchestrate to drive specific functions. Rapid advancements in microscopy, molecular biology, and genetics have improved the resolution and scale of our understanding of biological processes. Biophysical modeling techniques are often instrumental in obtaining physical insights, and provide predictive power to future experiments. My talk will use the developing fruit fly as an example model system, where life starts from an egg cell that gets fertilized and divides into multiple cells, which take different identities to make tissues, and ultimately deform into shapes to generate functional organs. I will illustrate multiscale computational models leveraging chemical engineering concepts and techniques including statistical mechanics, fluid dynamics, reaction engineering, and transport phenomena to both recreate and predict biological functions across scales. Finally, I will discuss an algorithm founded on polymer-physics theories to track chromosomal structures within DNA from real-time videos. Taken together, this talk will highlight the vital role of fundamental engineering principles to make the most of cutting-edge experimental data across biological contextsā€“ from molecules to tissues.